李法财
系 所:预防兽医学系
职 称:副教授
电子邮箱:li78561270@163.com
讲授课程:本科课程:《兽医寄生虫病学》等。
研究生课程:《兽医寄生虫病学》《人畜共患病》等。
个人简介
李法财,男,山东潍坊人,农学博士。主要从事动物寄生虫学的教学、科研以及科技开发与社会服务等工作,主要研究方向为人兽共患原虫。ㄈ绻纬妫┘靶笄葜匾娌。ㄈ缜虺妫┑姆肿恿餍胁⊙,免疫学、致病机制及防控策略等。工作期间主持或参与了多项科研项目,包括国家自然科学基金项目青年基金项目1项,亚愽全站网页版博士基金项目等。在《International Journal for Parasitology》、《Parasites & Vectors》、《Frontiers in Microbiology》等国内外期刊发表多篇论文。
研究领域
主要从事人畜共患病原微生物的致病机制及防控等研究。
科研项目
1.弓形虫α-AMY1调控支链淀粉分解及对缓殖子发育的功能研究,国家自然科学基金青年基金,31802182,2019-2021年,主持;
2.弓形虫USP调控支链淀粉合成及对速/缓殖子转换的功能研究,亚愽全站网页版博士基金,SWU119030,主持;
3.畜禽重要胞内寄生原虫的寄生与免疫机制研究,国家重点研发项目,2017YFD0500403,参与。
代表成果
代表论文:
1.Li FC*, Nie LB, Elsheikha HM, Yin FY, Zhu XQ*. Lysine crotonylation is widespread on proteins of diverse functions and localizations in Toxoplasma gondii. Parasitol Res. 2021, 120:1617-1626.
2.Nie LB, Liang QL, Elsheikha HM, Du R*, Zhu XQ*, Li FC*. Global profiling of lysine 2-hydroxyisobutyrylome in Toxoplasma gondii using affinity purification mass spectrometry. Parasitol Res. 2020, 119:4061-4071.
3.Nie LB, Liang QL, Du R*, Elsheikha HM, Han NJ, Li FC*, Zhu XQ*. Global Proteomic Analysis of Lysine Malonylation in Toxoplasma gondii. Front Microbiol. 2020 Apr 28;11:776. doi: 10.3389/fmicb.2020.00776.
4.Li FC*, Liu Q, Elsheikha HM, Yang WB, Hou JL, Zhu XQ. Identification of two novel host proteins interacting with Toxoplasma gondii 14-3-3 protein by yeast two-hybrid system. Parasitol Res. 2018, 117:1291-1296.
5.Liu Q, Li FC*, Zhou CX, Zhu XQ*. Research advances in interactions related to Toxoplasma gondii microneme proteins. Exp Parasitol. 2017, 176:89-98.
6.Liu Q, Li FC*, Elsheikha HM, Sun MM, Zhu XQ. Identification of host proteins interacting with Toxoplasma gondii GRA15 (TgGRA15) by yeast two-hybrid system. Parasit Vectors. 2017, 10:1.
7.Li FC, Gasser RB, Lok JB, Korhonen PK, He L, Di WD, Yin FY, Zhou R, Zhou YQ, Zhao JL, Hu M. Molecular characterization of the Haemonchus contortus phosphoinositide-dependent protein kinase-1 gene (Hc-pdk-1). Parasit Vectors. 2016, 9:65.
8.Li FC, Gasser RB, Lok JB, Korhonen PK, Wang YF, Yin FY, He L, Zhou R, Zhao JL, Hu M. Exploring the role of two interacting phosphoinositide 3-kinases of Haemonchus contortus. Parasit Vectors. 2014, 7:498.
9.Li F, Lok JB, Gasser RB, Korhonen PK, Sandeman MR, Shi D, Zhou R, Li X, Zhou Y, Zhao J, Hu M. Hc-daf-2 encodes an insulin-like receptor kinase in the barber's pole worm, Haemonchus contortus, and restores partial dauer regulation. Int J Parasitol. 2014, 44:485-96.